2005-2013 Mercedes-Benz R-Class (W251) fuse box diagram

The Mercedes-Benz R-Class (W251) was a mid-size luxury SUV/MPV produced between 2005 and 2013. If you’re looking for fuse box diagrams for models like R280, R300, R320, R350, R500, R550, and R63 from these years, this article provides detailed information. You’ll discover where the fuse panels are located inside the vehicle and learn about the function of each fuse and relay. This guide aims to simplify understanding of how to locate and manage these components in your Mercedes-Benz R-Class.

Cigar lighter (power outlet) fuses in the Mercedes-Benz R-Class are the fuses #43, #44, #45 and #46 in the Luggage Compartment Fuse Box.

Engine Compartment

2005-2013-Mercedes-Benz-R-Class-W251-engine-compartment-fuse-box-diagram-carsfuse.com
Fuse NumberFused functionFuse Amp
100Wiper motor30
101up to 2008:
AAC with integrated control additional fan motor
Valid for engines 113, 272: Purge control valve
Valid for engine 272:
Radio interference suppression capacitor 1
Radio interference suppression capacitor 2
Cylinder 1-6 ignition coil

Valid for engine 642:
O2 sensor upstream of CAT
CDI control unit
as of 2009:
Engine and air conditioning electric suction fan with integrated control
Valid for engine 272, 273:
Purging switchover
Circuit 87 M1e connector sleeve
Valid with engine 642:
CDI control unit
O2 sensor upstream of CAT
Valid for engine 642.870/872:
O2 sensor upstream of CAT
15
102up to 2008:
Valid for engine 642:
Recirculation pump for transmission oil cooler
Valid for engine 156:
Engine coolant circulation pump
as of 2009:
Valid for engine 642, engine 642.870 up to 31.7.10:
Transmission cooler circulation pump
Valid with engine 276:
Charge air cooler circulation pump
15
103up to 2008:
Valid for engine 113:
ME-SFI [ME] control unit
Cylinder 1-8 fuel injection valve

Valid for engine 642:
CDI control unit
as of 2009:
Valid for engine 642.950, 642.870/872: CDI control unit
Valid for engine 272: ME-SFI [ME] control unit
Valid with engine 276:
ME-SFI [ME] control unit
Engine/engine compartment connector
25
104up to 2008:
Valid for engine 113:
Left O2 sensor upstream TWC [KAT]
Right oxygen O2 sensor upstream of catalytic converter
Left O2 sensor downstream TWC [KAT]
Right O2 sensor downstream TWC [KAT]
Variable intake manifold switchover valve
EGR vacuum transducer
Air pump change-over valve
Valid for engine 272:
Heating system shutoff valve
Intake manifold tumble flap switchover valve
Air pump change-over valve
Three-disk thermostat valve
Pressure regulating on the valve power steering unit pump
Valid for engine 642:
Left hot film mass air flow sensor
Right hot film mass air flow sensor
Intake port shutoff motor
Glow time output stage
Vent line heater element
Power steering pump pressure regulator valve
Left exhaust gas recirculation positioner
Boost pressure positioner
as of 2009:
Valid for engine 272, 273: Connector sleeve, circuit 87 M2e
Valid for engine 642.950: Circuit 87 connector sleeve
Valid for engine 642.870/872: Circuit 87D2 connector sleeve
15
105up to 2008:
Valid for engine 113:
ME control unit
Radio interference suppression capacitor 1
Radio interference suppression capacitor 2
Cylinder 1-8 ignition coil

Valid for engine 272:
ME control unit
Hot film mass air flow sensor
Hall sensor for left inlet camshaft
Right intake camshaft Hall sensor
Left exhaust camshaft Hall sensor
Right exhaust camshaft Hall sensor
Left intake camshaft solenoid
Right camshaft intake solenoid
Left exhaust camshaft solenoid
Right exhaust camshaft solenoid
Cylinder 1-6 fuel injection valve

Valid for engine 642: CDI control unit
as of 2009:
Valid for engine 272, 273:
ME-SFI [ME] control unit
Circuit 87 M1i connector sleeve
Valid with engine 276: Engine/engine compartment connector
Valid for engine 642.950:
CDI 1.0 PK control unit
Engine compartment/interior compartment connector
Valid for engine 642.870/872:
CDI control unit
Engine compartment/interior compartment connector
Circuit 87 connector sleeve
15
106
107Valid for engine 113, 272, 273: Electric air pump40
108AIRmatic compressor unit 40
109ESP control unit 25
110Alarm signal horn with additional batteryAlarm siren10
111Intelligent servo module for DIRECT SELECT 30
112Left front lamp unit
Right front lamp unit
7.5
113Left fanfare horn
Right fanfare horn
15
114up to 2008:
Front SAM control unit
Valid for engine 272: ME control unit
as of 2009: Front SAM control unit
5
115ESP control unit5
116Electric controller unit (VGS) 7.5
117Distronic (DTR) controller unit 7.5
118Valid for engine 272, 273, 276: ME control unit
Valid for engine 642: CDI control unit
5
119Valid for engine 642.870/872: CDI control unit5
120up to 2008:
Valid for engine 113, 272: ME control unit
Valid for engine 642: CDI control unit
as of 2009:
Valid for engine 272, 273, 276:
Engine circuit 87 relay
ME-SFI [ME] control unit
Valid with engine 642: Engine circuit 87 relay
10
121STH heater unit20
122Valid for engine 113, 272, 273, 276, 642: Starter25
123Valid for diesel engine as of 1.9.08: Fuel filter condensation sensor with heating element20
124as of 2009: Electrohydraulic power steering7.5
125
Relays
AWiper stage 1 and 2 relay
BWiper ON / OFF
CValid for engine 642: Additional circulation pump for transmission oil cooling
Valid for engine 156: Engine coolant circulation pump
DTerminal 87 engine
ESecondary air injection pump
FHorn
GAir suspension compressor
HCircuit 15
IStarter

Front Pre-fuse box

2005-2013-Mercedes-Benz-R-Class-W251-front-pre-fuse-box-diagram-carsfuse.com
Fuse NumberFused functionFuse Amp
4
5Valid as of 1.7.09: ESP control unit40
6Valid up to 30.6.09: ESP control unit40
6Valid as of 1.7.09: Electrohydraulic power steering100
7AAC with integrated control additional fan motor100
8Engine compartment fuse and relay box150

Instrument Panel

2005-2013-Mercedes-Benz-R-Class-W251-instrument-panel-fuse-box-diagram-carsfuse.com
Fuse NumberFused functionFuse Amp
10Booster blower electronic blower controller10
11Instrument cluster5
12Automatic air conditioning [KLA] control and operating unit
Comfort automatic air conditioning [KLA] control and operating unit
15
13Upper control panel control unit
Steering column module
5
14CD changer (up to 2008)
EZS control unit
7.5
15Electronic compass
Media interface control unit (as of 2009)
5
16
17
18

Battery compartment pre-fuse box

2005-2013-Mercedes-Benz-R-Class-W251-battery-compartment-pre-fuse-box-diagram-carsfuse.com
Fuse NumberFused functionFuse Amp
78Diesel engine: Heater booster control unit150
79Rear SAM control unit60
80Rear SAM control unit60
81as of 2009:
Valid for engine 642.870: AdBlue® supply relay
Valid with engine 276: Engine compartment fuse and relay box
40
82up to 2008: Load compartment fuse and relay box150
82as of 2009: Load compartment fuse and relay box100
83USA version: WSS (Weight Sensing System) control unit5
84Restraint systems control unit10
85as of 2009: DC/AC converter control unit (115 V socket)25
86Cockpit fuse box30
8730
88up to 2008: Front SAM control unit70
88as of 2009: Front SAM control unit40
89Front SAM control unit70
90Front SAM control unit70
91Blower regulator40

Luggage Compartment

2005-2013-Mercedes-Benz-R-Class-W251-fuse-box-luggage-compartment-up-to-31-05-2006-diagram-carsfuse.com
Up to 31.05.2006
2005-2013-Mercedes-Benz-R-Class-W251-luggage-compartment-as-of-01-06-2006-fuse-box-diagram-carsfuse.com
As of 01.06.2006
Fuse NumberFused functionFuse Amp
20Interference suppression filter for radio antenna
Microphone array control unit (up to 2008; except Japan version)
Voice control system (VCS [SBS]) control unit (up to 2008; USA version)
5
21RCP [HBF] control unit5
22Parktronic system (PTS) control unit
Stationary heater (STH)
radio remote control receiver (as of 2009)
5
23DVD player (rear entertainment system)
E-net compensator
Rear audio control unit (up to 2008)
Portable CTEL separation point (up to 2008; Japan version)
Universal Portable CTEL Interface (UPCI [UHI]) control unit (up to 2008; Japan version)
COMAND operating, display and controller unit (as of 2009)
10
24Right front reversible emergency tensioning retractor40
25up to 2008:
Radio (except USA version and Japan version)
Radio and navigation unit (except USA version and Japan version)
COMAND operating, display and controller unit
15
25as of 2009:
Radio
Radio and navigation unit
COMAND operating, display and controller unit
20
26Right front door control unit25
27Front passenger seat adjustment comfort relay (up to 2008) Passenger-side front seat adjustment control unit with memory30
28Driver seat adjustment comfort relay (up to 2008) Driver-side front seat adjustment control unit, with memory30
29Left front reversible emergency tensioning retractor40
30up to 2008:
Valid for engine 156:
Left fuel pump control unit
Right fuel pump control unit
as of 2009: Fuel system control unit
40
31HS [SIH], seat ventilation and steering wheel heater control unit10
32AIRmatic with ADS control unit Rear axle level control system control unit15
33Keyless Go control unit25
34Left front door control unit25
35Amplifier for sound system Subwoofer amplifier (as of 2009)30
36up to 2008: Emergency call system control unit5
36up to 2008:
Japan version:
VICS+ETC voltage supply separation point
as of 2009: Emergency call system control unit
10
37Backup camera voltage supply module (as of 01.06.2006, except USA version and Japan version)
Backup camera control unit (as of 01.06.2006, Japan version)
5
38Audio gateway control unit (up to 2008; Japan version)
Digital TV tuner
TV combination tuner (analog/digital)
10
39up to 2008:
SDAR control unit (USA version)
Tire pressure monitor (TPM) [RDK] control unit
as of 2009:
Tire pressure monitor (TPM) [RDK] control unit
High definition tuner control unit
Digital Audio Broadcasting control unit
External navigation separating point (South Korea version)
7.5
40up to 2008: Rear-end door closing control unit40
40as of 2009: Rear-end door closing control unit30
41Overhead control panel control unit25
42Overhead control panel control unit25
43Up to 31.05.2006:
Tailgate wiper motor
Left 3rd seat row socket
Right 3rd seat row socket
as of 2009:
Valid for engine 272, 273, 276: Fuel system control unit
Valid for engine 642.872: Right fuel system control unit
20
44Up to 31.05.2006:
Left 2nd seat row socket
Right 2nd seat row socket
as of 2009:
USA version:
Front interior socket
115 V socket
20
45up to 2008:
Cargo area connector box
up to 31.05.2006:
Front interior socket
as of 01.06.2006:
Left 2nd seat row socket
Right 2nd seat row socket
as of 2009:
Right 2nd seat row socket
Luggage compartment socket
20
46Front cigar lighter with ashtray illumination15
47as of 2009:
Valid for retrofit:
Left front illuminated door sill molding
Right front illuminated door sill molding
10
48as of 2009:
Valid for engine 642.870: AdBlue® supply relay
5
49Right antenna coil (up to 2008)
Heated rear window
30
50up to 2008: Tailgate wiper motor10
50as of 2009: Tailgate wiper motor15
51Activated charcoal filter shutoff valve5
53AIRmatic with ADS control unit
Rear axle level control system control unit
up to 2008:
Valid for engine 156:
Left fuel pump control unit
Right fuel pump control unit
as of 2009:
Valid for engine 272, 273, 276: Fuel system control unit
Valid for engine 642.872: Right fuel system control unit
5
54Front SAM control unit
Headlamp range adjustment control unit (bi-xenon headlamp unit)
5
55Rotary light switch
Instrument cluster
7.5
56up to 2008: Data link connector
as of 2009: Valid for engine 642.870: AdBlue control unit
5
57up to 2008: Fuel pump with fuel gauge sensor
as of 2009: Valid for engine 642.870: Fuel pump
20
58Data link connector
Central gateway control unit
7.5
59Driver NECK-PRO head restraint solenoid
Front passenger NECK-PRO head restraint solenoid
7.5
60up to 2008:
Glove compartment illumination with switch
Rear SAM control unit
Engine compartment fuse and relay box
CTEL separation point
VICS+ETC voltage supply separation point (Japan version)
Emergency call system control unit
as of 2009:
Glove box illumination with switch
Engine compartment fuse and relay box
Rear SAM control unit)
Cell phone separation point
VICS+ETC power supply separating point (Japan version)
Multicontour seat pneumatic pump
External navigation separating point (South Korea version)
Emergency call system control unit
Rear bumper interior Blind Spot Monitoring electrical connector
5
61Restraint systems control unit
Right front seat contacting strip
10
62Front passenger seat adjustment switch
Front passenger lumbar support regulator control unit
30
63Driver seat adjustment switch
Driver lumbar support regulator control unit
30
64
65
66as of 2009: Multicontour seat pneumatic pump30
67Rear air conditioning blower motor25
68up to 2008: Heated rear seats
as of 2009: Seat heater, seat ventilation and steering wheel heater control unit
25
6930
70Trailer hitch socket (13-pin)
Trailer hitch socket (7-pin) (USA version)
20
71USA version: Electric brake control separation point30
72Trailer hitch socket (13-pin)15
Relays
Kto 31.05.2006: Terminal 15R power outlet relay, with power-down
as of 01.06.2006: Relay, circuit 15R sockets (with power-down) (power supply of electric seat adjustment)
LTerminal 30X
MHeated rear window relay
NCircuit 15 relay / terminal 87FW
OFuel pump relay
PRear wiper relay
RCircuit R relay 15R
SReserve 1 (changer) (power supply for front socket)
Tas of 01.06.2006: Reserve 2 (normally open contact) (power supply for center and rear sockets)
Uas of 01.06.2006: Trailer relay terminal 30
Vas of 01.06.2006: Spare relay 2
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Tom Smith is a passionate car mechanic and automotive enthusiast, specializing in the intricate world of car fuse boxes. With years of hands-on experience under the hood, he has earned a reputation as a reliable expert in his field. As the founder and content creator of the popular blog website 'carsfuse.com,' Tom has dedicated himself to sharing his extensive knowledge of car fuse boxes and electrical systems with the world.

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